Polymeric nanoparticles may prove beneficial for patients suffering from asthma, cystic fibrosis or lung disease, human immunodeficiency virus (HIV), cancer or those who are exposed to corticosteroid drugs for a long time.
Polymeric Nanoparticles
Nanoparticles are promising for controlled and effective release of drugs. Polymeric nanoparticles are very good for drug delivery. Azole drugs used today cure the infection. However, resistance to existing antifungal drugs is a concern and hence better methods of drug delivery are needed so that the drugs can be effective for treating infections.
Department of Science and Technology Report
A team of scientists from the Agharkar Research Institute, an autonomous institute of the Department of Science and Technology (DST), found that drug-loaded nanoparticles inhibit the growth of Aspergillus spp. and were effective against the fungal infection called aspergillosis caused by Aspergillus flavus and Aspergillus fumigatus fungi.
The nanoformulation was found to be free from cytotoxic and hemolytic effects. The ARI team is hopeful about the application of the method in the development of inhalation nanoformulations against pulmonary aspergillosis. The research, led by scientist Dr Vandana Ghormade and PhD student Kamal Mayattu, was published in the journal Zeitschrift für Naturforschung C.
There is hope for further expanding the scope of antifungal nano formulations and the possibility of public-private partnerships for commercialization in the future. Polymeric nanoparticles are nanoscale sized objects made from polymers such as polyethylene glycol (PEG) or polylactide-co-glycolide (PLGA), which are used in in vitro delivery of therapeutic and diagnostic agents, as well as in many additional biomedical functions. In this article AZoNano covers the main properties and applications of polymeric nanoparticles.
Polymeric Nanoparticles Polyethylene Glycol
Polymeric nanoparticles are nanoscale-sized objects made from polymers such as polyethylene glycol (PEG) or polylactide-co-glycolide (PLGA). They are used in the in vitro delivery of therapeutic and diagnostic agents, as well as a number of additional biomedical functions. In this article, AZoNano covers the main properties and applications of polymeric nanoparticles.
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