A new research in Japan has found that the cause of colorectal cancer (CRC) disease is related to liver disease somewhere. There are many types of liver disease. Due to which there can also be a lot of alcohol. According to a research published in ‘Clinical Gastroenterology and Hepatology’, people who drink a lot of alcohol. They are given a lot of emphasis on screening cancer. Both alcoholic and non-alcoholic fatty liver disease (NAFLD) are considered a risk factor for colorectal cancer. One of the main causes of cancer is one of the main causes.
CRC risk increases in people with liver disease
Dr. Tekfumi Kimura of Japan’s Tashinshu University School of Medicine led a nationwide population-based study in association with Dr. Nobuharu Tamaki and Dr. Shun-Ichi Vakabayi. Research analyzed data of 6.38 million individuals to compare CRC risk in people with SLD patients and people with liver disease. The results showed that CRC developed in 0.19% of patients over a period of 4.5 years. However, the risk between the SLD groups was quite different.
1.73 times more than patients with liver disease
ALD patients had the highest risk – 1.73 times more than people with liver disease. Researchers believe that different mechanisms can explain why some liver disease groups have a high risk of colorectal cancer.
Drinking excessive alcohol in CRC can damage DNA. Oxidative stress can occur and a lot of dirt can be produced in the body. Which can cause many cancer disease. Metabolic dysfunction and inflammation – Masld/Nafld has a deep connection with obesity, insulin resistance and chronic inflammation, which are all known to contribute to the development of cancer. Dr. Kimura emphasizes that it is important to find out timely to improve the results of the patient.
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Colorectal cancer increases risk
Identification and examination of patients with high risk SLDs of colorectal cancer development can help in detecting and improve the patient’s results. ALD and Metald focuses on patients’ require the requirement of advanced CRC screening programs.
This research gives strong evidence that alcohol and metabolic dysfunction play individual and joint role in increasing the risk of colorectal cancer. Moving forward, doctors should prefer regular CRC screening for patients with liver disease, especially for patients with ALD and Metald groups.
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